In a recent study published in the journal Scientific Reports, two-dimensional biocompatible and elastic plasmonic contact lenses were fabricated using polydimethylsiloxane (PDMS).
Research: Two-dimensional biocompatible plasma contact lenses for color blindness correction.
Here, an inexpensive basic design for correcting red-green color blindness was designed and tested based on mild nanolithography.
Human color perception is derived from three cone-shaped photoreceptor cells, long (L), medium (M), and short (S) cones, which are essential for seeing red, green, and blue tones, with a spectral sensitivity maximum of 430, 530 and 560 nm, respectively.
Color blindness, also known as color vision deficiency (CVD), is an eye disease that hinders the detection and interpretation of different colors by three photoreceptor cells that function in normal vision and operate according to their spectral sensitivity maxima.This eye disease, which may be constrictive or genetic, is caused by a loss or defect in cone photoreceptor cells.
Schematic diagram of the fabrication process of the proposed PDMS-based lens, (b) images of the fabricated PDMS-based lens, and (c) immersion of the PDMS-based lens in HAuCl4 3H2O gold solution for different incubation times .© Roostaei, N. and Hamidi, SM (2022)
Dichroism occurs when one of the three cone photoreceptor cell types is completely absent; and is classified as proteophthalmia (no red cone photoreceptors), deuteranopia (no green cone photoreceptors), or trichromatic Color blindness (lack of blue cone photoreceptors).
Monochromaticity, the least common form of color blindness, is characterized by the absence of at least two cone photoreceptor cell types.
Monochromatics are either completely colorblind (colorblind) or only have blue cone photoreceptors.A third type of abnormal trichromacy occurs if one of the cone photoreceptor cell types malfunctions.
Aberrant trichromacy is divided into three types based on the type of cone photoreceptor defect: deuteranomaly (defective green cone photoreceptors), protanomaly (defective red cone photoreceptors), and tritanomaly (defective blue cone photoreceptors) photoreceptor cells).
Protans (protanomaly and protanopia) and deutans (deuteranomaly and deuteranopia), commonly known as protanopia, are the most typical types of color blindness.
Protanomaly, the spectral sensitivity peaks of red cone cells are blue-shifted, while the sensitivity maxima of green cone cells are red-shifted.Due to the conflicting spectral sensitivities of green and red photoreceptors, patients cannot distinguish the different hues.
Schematic diagram of the fabrication process of the proposed PDMS-based 2D plasmonic contact lens, and (b) real image of the fabricated 2D flexible plasmonic contact lens.© Roostaei, N. and Hamidi, SM (2022)
While there has been a lot of valuable work in developing foolproof treatments for color blindness based on several medical avenues for this condition, major lifestyle adjustments remain an open debate.Gene therapy, tinted glasses, lenses, optical filters, optoelectronic glasses, and enhancements on computers and mobile devices are topics covered in previous research.
Tinted glasses with color filters have been thoroughly researched and appear to be widely available for CVD treatment.
While these glasses are successful in increasing color perception for colorblind people, they have disadvantages such as high price, heavy weight and bulk, and lack of integration with other corrective glasses.
For CVD correction, contact lenses developed using chemical pigments, plasmonic metasurfaces, and plasmonic nanoscale particles have been recently investigated.
However, these contact lenses face many obstacles, including lack of biocompatibility, limited use, poor stability, high price, and complex production processes.
The present work proposes two-dimensional biocompatible and elastic plasmonic contact lenses based on polydimethylsiloxane (PDMS) for color blindness correction, with special emphasis on the most common color blindness, deuterochromatic anomaly (red- green) color blindness.
PDMS is a biocompatible, flexible and transparent polymer that can be used to make contact lenses.This harmless and biocompatible substance has found a variety of uses in the biological, medical and chemical industries.
In this work, 2D biocompatible and elastic plasmonic contact lenses made of PDMS, which are inexpensive and straightforward to design, were developed using a mild nanoscale lithography approach, and deuteron correction was tested.
The lenses are made from PDMS, a hypoallergenic, non-hazardous, elastic and transparent polymer.This plasmonic contact lens, based on the phenomenon of plasmonic surface lattice resonance (SLR), can be used as an excellent color filter for correcting deuteron anomalies.
The proposed lenses have good properties such as durability, biocompatibility and elasticity, making them suitable for color blindness correction applications.
Post time: Jun-23-2022
